What is Cathelicidin?
Cathelicidin is a family of naturally occurring antimicrobial peptides (AMPs) that form an important part of the body's innate immune system. In humans, the primary cathelicidin peptide is known as LL-37, which is produced by immune cells and epithelial cells in the skin, respiratory tract, gastrointestinal tract, and other tissues.
Cathelicidins help protect the body against bacteria, viruses, fungi, and other microorganisms. They also play important roles in immune regulation, wound healing, inflammation, and tissue repair. Because of these biological functions, Cathelicidin peptides are widely studied in immunology, infectious disease, dermatology, and regenerative medicine research.
Chemical Information
Generic Name: Human Cathelicidin (LL-37)
Common Name: Cathelicidin
Category: Antimicrobial Peptide (AMP)
Peptide Type: Host Defense Peptide
Amino Acid Length: 37 Amino Acids (LL-37)
Chemical Formula (LL-37): C₂₀₅H₃₄₀N₆₀O₅₃
Molecular Weight: Approximately 4493.3 g/mol
Type: Naturally occurring antimicrobial peptide (also produced synthetically for research)
What is Cathelicidin Studied For?
Cathelicidin is widely researched for its potential role in:
- Innate immune defense
- Antibacterial activity
- Antiviral activity
- Antifungal activity
- Wound healing
- Skin regeneration
- Inflammation research
- Tissue repair
- Immune system regulation
- Respiratory health research
- Gastrointestinal health research
- Dermatology research
How Does Cathelicidin Work?
Cathelicidin is produced by immune cells as part of the body's first line of defense against infection.
Research suggests it may work by:
- Disrupting the membranes of bacteria and other microorganisms
- Helping eliminate pathogens
- Regulating inflammatory responses
- Recruiting immune cells to sites of infection
- Supporting tissue repair and wound healing
- Promoting skin barrier function
- Assisting in the formation of new blood vessels during healing
These mechanisms are still being investigated, particularly in clinical research.
Who Uses It?
Cathelicidin has primarily been studied in:
- Immunology researchers
- Infectious disease researchers
- Dermatology researchers
- Wound-healing researchers
- Regenerative medicine researchers
- Laboratory scientists studying innate immunity
Outside research settings, Cathelicidin is not approved as a routine therapeutic medication.
Age Group
Research generally involves:
Adults aged 18 years and older
Some laboratory and clinical studies may involve different populations depending on the research objectives, but most investigational studies focus on adults.
Potential Benefits
Current research suggests Cathelicidin may help support:
✔ Natural antimicrobial defense
✔ Healthy immune function
✔ Wound healing
✔ Tissue repair
✔ Skin regeneration
✔ Healthy inflammatory response
✔ Skin barrier function
✔ Protection against microbial infections
✔ Connective tissue recovery
✔ Overall immune system research
These potential benefits remain under scientific investigation, and additional clinical studies are required to confirm their effectiveness in humans.
Possible Side Effects
Human safety data remain limited. Reported or potential side effects may include:
- Injection-site irritation
- Mild redness
- Temporary swelling
- Skin sensitivity
- Mild discomfort
- Temporary fatigue
- Headache
- Allergic reactions (rare)
Because Cathelicidin remains an investigational peptide, the complete safety profile has not yet been established.
Administration
In research settings, Cathelicidin has been investigated using:
- Subcutaneous (SC) injection
- Intramuscular (IM) injection
- Topical formulations
- Laboratory research applications
The route of administration depends on the specific research protocol.
Dosage
There is no established or approved dosage for routine human use.
Dosage varies according to the research protocol.
Product Information
- Quantity: 0.10g (100mg)
- Purity: >99%
- Grade: Lab Grade
The amount contained in this vial does not represent a recommended human dose.
Is Cathelicidin a Steroid?
No.
Cathelicidin is not a steroid.
It is a naturally occurring antimicrobial peptide involved in the body's innate immune defense.
Does Cathelicidin Help Fight Infections?
Research suggests Cathelicidin possesses broad-spectrum antimicrobial activity against certain bacteria, viruses, and fungi by helping the immune system control microbial growth.
However, more clinical studies are needed to determine its effectiveness as a therapeutic treatment in humans.
Does Cathelicidin Support Wound Healing?
Research indicates Cathelicidin may contribute to wound healing by promoting tissue repair, regulating inflammation, and supporting the formation of new blood vessels.
While laboratory findings are promising, additional human clinical research is required.
Does Cathelicidin Boost Immunity?
Cathelicidin is an important component of the innate immune system and plays a role in the body's natural defense mechanisms.
Current research is investigating how it may help regulate immune responses rather than simply "boost" immunity.
Storage
- Store refrigerated at 2°C–8°C (36°F–46°F)
- Do not freeze
- Protect from direct sunlight
- Keep in a clean, dry environment
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